Frequency of prion genotypes in Cikta sheep
DOI:
https://doi.org/10.17205/SZIE.AWETH.2020.2.131Keywords:
scrapie resistance, Cikta, Zaupel, breed conservationAbstract
The authors study the current status of Hungarian Cikta Sheep based on genetic background of scrapie resistance. The aim of this investigation was to estimate the relative frequency of prion haplotypes, -genotypes, and risk categories as well as to reveal the efficiency of scrapie eradication program achieved over the last decade.
The authors confirmed based on larger sample size the previous knowledge, that the resistance against scrapie of Cikta breed is considered as low, and the classification of this breed according to risk category has not been improved. However, the frequent haplotype ARQ and risk category 3 can also be considered for breed specificity. The careful breeding of them is permitted and will contribute to the maintenance of breed diversity according to other aspects.
References
Adlung, R. (1912): Die Schafhaltung in Württemberg. Illustrierte landwirtschaftliche Zeitung (Berlin) 450–453.
Agrobiogen (2016): Scrapie Resistenz. Agrobiogen GmbH Biotechnologie. URL: http://www.agrobiogen.de. Accessed: 25 March 2016
Áldásy, P., Süveges, T. (1964): A juhok súrlókórjának hazai előfordulása. Magyar Állatorvosok Lapja 19. 463–465.
Álvarez, I., és mtsai (2007): Genetic diversity loss due to selection for scrapie resistance in the rare Spanish Xalda sheep breed. Livest Sci., 111. 204–212. https://doi.org/10.1016/j.livsci.2007.01.147
Álvarez, I., és mtsai (2009): Quantifying diversity losses due to selection for scrapie resistance in three endangered Spanish sheep breeds using microsatellite information. Prev Vet Med., 91. 172–178. https://doi.org/10.1016/j.prevetmed.2009.06.008
Baylis, M., és mtsai (2004): Risk of scrapie in British sheep of different prion protein genotype. J Gen Virol, 85. 2735–2470. https://doi.org/10.1099/vir.0.79876-0
Bohm, J. (1878): Die Schafzucht nach ihrem jetzigen rationellen Standpunkt. 2er Teil: Die Züchtung des Schafes. Verlag von Wiegandt, Hempel & Baren, Berlin
Bostedt, H., Dedié, K. (1996): Infektionsbedingte Erkrankungen des Gesamtorganismus. Viruskrankheiten. Traberkrankheit. In: Bostedt, H, Dedié K (eds) Schaf-und Ziegenkrankheiten Verlag Eugen Ulmer Stuttgart, pp. 73–75.
Brem, G., Graf, F., Kräußlich, H. (1982): Möglichkeiten der Anlage von Genreserven - genetische Probleme und Kosten. Bayerisches landwirtschaftliches Jahrbuch, München, Bodenkultur, 59. 380–383.
Cameron, C., és mtsai (2014): Prion protein genotypes of sheep as determined from 3343 samples submitted from Ontario and other provinces of Canada from 2005 to 2012. Can J Vet Res, 78. 260–266.
Dexler, H. (1931): Traberkrankheit. In: Stang V, Wirth D (eds) Tierheilkunde und Tierzucht. Eine Enzyklopädie der praktischen Nutztierkunde. Urban & Schwarzenberg, Berlin, Wien, 807 p.
Drögemüller, C., Leeb, T., Distl, O. (2001): PrP genotype frequencies in German breeding sheep and the potential to breed for resistance to scrapie. Vet Rec, 149. 349–352. https://doi.org/10.1136/vr.149.12.349
EC (2001): Regulation (EC) No 999/2001 of the European Parliament and of the Council of 22 May 2001 laying down rules for the prevention, control and eradication of certain transmissible spongiform encephalopathies
Feldmann, A., Bietzker, U., Mendel, C. (2005): Schafrassen in den Alpen. Gesellschaft zur Erhaltung alter und gefährdeter Haustierrassen, Witzenhausen, Deutschland
Fésüs, L., Zsolnai, A., Horogh, G., Anton I. (2004): A juhok surlókórja 2. Prion genotípus gyakoriságok hazai őshonos állományainkban. Magyar Állatorvosok Lapja, 126. 670–675.
Fésüs, L., Zsolnai, A., Anton, I., Sáfár, L. (2008): Breeding for scrapie resistance in Hungarian sheep population. Acta Vet Hung, 56. 173–180. https://doi.org/10.1556/avet.56.2008.2.4
Foster, J., Hunter, N. (1998): Transmissible spongiform encephalopathies: transmission, mechanism of disease, and persistence. Curr Opin Microbiol, 1. 442–447. https://doi.org/10.1016/S1369-5274(98)80063-5
Kang, H. E., Mo, Y., Abd Rahim, R., Lee, H. M., Ryou, C. (2017): Prion Diagnosis: Application of Real-Time Quaking-Induced Conversion. Review Article. Biomed Res Int, Article ID 5413936, 8 p. https://doi.org/10.1155/2017/5413936
Korth, J. C. E. D. (1825): Das Schaf und die Schafzucht in allen ihren Zweigen. Paulische Buchhandlung, Berlin
Nagy, B., és mtsai (2009): Association between PrP genotypes and selected growth traits of Hungarian Merino and German Mutton Merino rams. Archives of Animal Breeding, 52. 613–617. https://doi.org/10.5194/aab-52-613-2009
Rabenau, H. F. (2009): Teil III. Spezielle Mikrobiologische Diagnostik, 2 Prionen: 28 Diagnostik prionbedingter Erkrankungen, TSE-Erreger, Übertragungswege bei Tieren. In: Neumeister B, Geiss HK, Braun RW, Kimmig P (eds) Mikrobiologische Diagnostik - Bakteriologie - Mykologie - Virologie - Parasitologie. Georg Thieme Verlag, Stuttgart, New York, pp. 635–639.
Selbitz, H.J., Bisping, W. (1995): Tierseuchen und Zoonosen: alte und neue Herausforderungen, Gustav Fischer Verlag, Jena, Stuttgart
Stepanek, O., Horin, P. (2017): Genetic diversity of the prion protein gene (PRNP) coding sequence in Czech sheep and evaluation of the national breeding programme for resistance to scrapie in the Czech Republic. J. Appl. Genetics, 58. 111–121. https://doi.org/10.1007/s13353-016-0354-5
Downloads
Published
Issue
Section
License
Copyright (c) 2020 Kovács Endre, Tempfli Károly, Zenke Petra, Maróti-Agóts Ákos, Sáfár László, Gáspárdy András
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
