Klórpirifosz és a ciprodinil hatóanyagú növényvédő szerek együttes méreghatásának vizsgálata házityúk-embriókban
Keywords:
chlorpyrifos, cyprodinil, chicken embryo, embryonic mortality, developmental disorder, toxic interactionAbstract
Our study aimed to determine the individual and combined toxic effects of chlorpyrifos (480 g/l) insecticide (Pyrinex 48 EC) and cyprodinil (500 g/kg) fungicide (Chorus 50 WG) on the development of chicken embryos. The pesticides, 0.1 ml of 1% Pyrinex 48 EC and 0.125% Chorus 50 WG, were injected alone and together into the air chamber of the eggs before incubation. The chicken embryos were examined on the 19th day according to the following: embryonic mortality rate, type and rate of developmental abnormalities, and body weight. Embryonic mortality and developmental abnormalities were analysed with Fisher's exact test, body weight data with One-Way ANOVA, and Tukey and Dunnett tests. The combined use of Pyrinex 48 EC and Chorus 50 WG pesticides proved to be embryotoxic for chicken embryos. The incidence of embryonic mortality and embryonic developmental disorders increased when they were used simultaneously, and body weight of the embryos decreased. Pyrinex 48 EC and Chorus 50 WG had an additive effect on the embryonic mortality rate. Both pesticides were embryotoxic as confirmed by increased developmental abnormalities.
References
Budai, P., Fejes, S., Várnagy, L., Somlyay, I. M. and Kulcsár-Szabó, Z. 2003. Teratogenicity test of dimethoate containing insecticide formulation and Cd-sulphate in chicken embryos after administration as a single compound or in combination. Communications in Agricultural and Applied Biological Sciences 68. 795-798.
Damalas, C. A. and Eleftherohorinos, I. G. 2011. Pesticide exposure, safety issues, and risk assessment indicators. International journal of environmental research and public health 8(5). 1402-1419.
Darnell, D. K. and Schoenwolf, G. C. 2000. The chick embryo as a model system for analyzing mechanisms of development. Developmental Biology Protocols pp. 25-29.
Lehel, J., Szabó, R., Gajcsi, D., Jakab, C., Grúz, A., Kormos, E. and Budai, P. 2014. Investigation of toxic interaction of copper sulphate and chlorpyriphos on chicken embryo. Magyar Állatorvosok Lapja 136(8). 494-500.
Szabó, R., Major, L., Lehel, J., Saidon, N. B. and Budai, P. 2022. Teratogenicity testing of chlorpyrifos and tebuconazole in chicken embryos after simultaneous administration. Agrofor International Journal 7(1). 40-47.
Szemerédy, G., Kormos, E., Somody, G., Buda, I., Szabó, R., Lehel, J. and Budai, P. 2018. Teratogenicity test of individual and combined toxic effects of tebuconazole fungicide and leadacetate on chicken embryos. Acta Agraria Kaposváriensis 22(2). 25-32.
Várnagy, L., Budai, P., Fejes, S., Susan, M., Fáncsi, T., Keserű, M. and Szabó, R. 2003. Toxicity and degradation of metolachlor (Dual Gold 960 EC) in chicken embryos. Communications in Agricultural and Applied Biological Sciences 68. 807-811.
Downloads
Published
Issue
Section
License
Copyright (c) 2023 Szabó Rita, Varga Dorina, Budai Péter, Lehel József, Nadhirah Binti Saidon, Buda István, Major László
![Creative Commons License](http://i.creativecommons.org/l/by-nc-nd/4.0/88x31.png)
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.